Chapter 17, Page 2

Determining the cause

When trying to determine the cause of hirsutism, several blood tests need to be done to measure androgen levels. These tests are done by radioimmunoassay in a specialised laboratory, and include levels of: testosterone; androstendione; 17-hydroxyprogesterone; and DHEA-S (dehydroepiandrosterone sulphate).

These tongue-twisters are simply the chemical names of androgens produced in the body. Which particular hormone level is increased will tip off the doctor as to where the problem lies whether in the ovaries or in the adrenal glands. A pelvic ultrasound or special x-ray studies may also need to be done to detect ovarian or adrenal tumours. Hormone suppression or stimulation tests which further evaluate the function of the ovaries and adrenal glands may also be required. During these tests, blood is measured for hormone levels both before and after the administration of a specific hormone medication. For example, the ACTH (adrenocorticotropic hormone) stimulation test is conducted in order to check for the presence of late onset adrenal hyperplasia.

Treatment

Of course, the priority will be to correct the problem of infertility. Thus for example, if the problem of hirsutism is due to anovulation due to polycystic ovarian syndrome, the primary goal will be to induce ovulation.Low doses of steroids called dexamethasone or prednisone may also be prescribed if the adrenal gland is overactive. This medicine is usually taken at bedtime and serves to suppress production of the ACTH hormone which stimulates the adrenal gland.

Hormone treatment may prevent new hairs from developing. However, it usually takes many years for the excess hair to develop, and a significant decrease in the rate of hair growth will not be seen for at least six months of hormone treatment. Once hormone treatment has proven to be effective, it may be continued indefinitely. However, terminal hairs that are already present will not fall out or disappear with hormonal therapy and must be removed by other means.

Cosmetic therapy

For temporary hair removal, many women with mild hirsutism pluck the unwanted hairs. Waxing, another alternative, is essentially the same as plucking.

Depilating agents are chemicals that dissolve the hair shafts on both facial and body hair and may also be used to remove unwanted hair. These chemicals can cause irritation and facial skin is particularly sensitive.

Shaving is probably the simplest and safest temporary hair removal procedure. Although frequently required, it is virtually painless and seldom has side effects. Contrary to popular belief, shaving does not make hair grow faster. An electric razor produces less skin irritation than a blade.

Electrolysis is the only permanent way to remove unwanted hair. During this procedure, a very fine needle is placed next to the hair shaft into the follicle. A mild electric current is sent through the needle and permanently kills the hair follicle. It is not possible to use this technique to remove hairs from very large areas of the body because each hair must be treated individually. In addition, the technique, although quite effective, is expensive, time consuming, and moderately uncomfortable. If hormonal therapy is being started, it is best to delay electrolysis for at least six months so that the growth of new terminal hairs will be reduced.

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Credits: How to Have a Baby: Overcoming Infertility