Luteal Phase Defect (LPD), Page 2

Luteal Phase Defect

Definition

Ovulatory dysfunction effecting the second half of the menstrual cycle, also referred to as inadequate or insufficient luteal phase

Caused by

Hormonal imbalance(s)

Results in

Development of uterine lining that is out of phase with the fertilized egg and resulting inappropriate implantation

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Diagnosis/Treatment

Dx
Testing hormone levels through blood draws & specially-timed endometrial biopsy
Tx
Hormone therapies such as progesterone supplements, hCG, GnRH, clomiphene citrate

More simply stated, LPD is a hormonal imbalance, effecting ovulatory function and uterine endometrial lining, which can increase a woman's risk of both conception difficulties and early miscarriage. The "gold standard" of diagnostic techniques for LPD is the endometrial biopsy, which is performed to see if the two cycles are "in sync". One young mom, Angela, gives the example of her experience with an endo biop: "When I was diagnosed with LPD, my uterine lining was dated at day 22, but my period started the next day...".

The balancing of a woman's reproductive hormones is a delicate matter easily effected by a variety of factors. LPD is detectable and treatable, but only if the medical provider knows what to look for in the diagnostic phase. A patient who has her basal body temperature chart handy may be able to provide important clues to her physician regarding her own luteal phase. Staying keenly aware of her body's other monthly changes will enhance her diagnosis.

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